OAHP will also support the Accelerated Access Collaborative through its research infrastructure, including OAHP’s:
- NIHR Applied Research Collaborative (ARC) that supports research programmes integrating health and social care with mental health. This includes work on disease prevention, digital tools and implementation science across entire patient pathways.
- NIHR Medtech and In Vitro Diagnostics Co-Operative (MIC) includes a specific horizon scanning function, the Oxford Diagnostic Horizon Scan Programme that identifies new and emerging diagnostic technologies relevant to primary care in the NHS.
AND its work in partnership with the Oxford AHSN and other AHSCs and AHSNs as outlined below:
OAHP supports AHSN projects, providing research evidence to promote adoption. OAHP researchers pioneered the evaluation and adoption of PIGF testing in pregnant women at risk of pre-eclampsia. This work was recognised in 2019 by an HSJ Partnership Award and a Univants of Healthcare Excellence Award, followed by NHSE funding from the Innovation and Technology Payment (ITP) and the AAC to promote adoption of PlGFbased testing for pre-eclampsia in all NHS hospital trusts nationally.
OAHP has national collaborations including those with current AHSCs and with Academic Health Partnerships such as Birmingham Health Partners, forming the ‘M40 Alliance’ that brings together clinical researchers from centres across Oxford and Birmingham and University Hospitals in Coventry and Warwick. The M40 Alliance leverages complementary strengths from large metropolitan populations with cutting-edge basic science and novel treatments. The Arthritis Therapy Acceleration Programme (A-TAP) brings together basic science with
translational research capabilities in orthopaedics and rheumatology (OUH, OBU) with the Institute of Translational Medicine (University of Birmingham) and commercial partners. In Haematology, the OAHP-Birmingham collaboration has delivered 15 national Phase I-III clinical trials, including state-of-the-art single cell genomics.
Through the national Therapy Acceleration Programme and the IMPACT Program, these trials have brought novel therapies to NHS patients pre-approval, leveraged £55M of drugs, established precision medicine in routine NHS pathways, improving outcomes and saving costs.
In partnership with Imperial AHSC, OAHP leads CHERUB (Collaborative HIV Eradication of Viral Reservoirs: UK BRC) bringing together internationally leading researchers from five NIHR BRCs in a UK-wide programme, targeting the objective of HIV eradication.
OAHP (Prof Alan Stein) works with A Better Start Blackpool, a multimillion National Lottery-funded programme promoting good early childhood development. This includes development of psychological interventions for mothers with perinatal depression and improving family communication in the context of parental illness.
OAHP hosts and leads the NIHR-BHF Cardiovascular Partnership, that fosters collaboration between research programmes and capabilities (cohorts, imaging, bioresources) across all BRCs and UK British Heart Foundation (BHF) Centres.
The NIHR Mental Health Translational Research Collaboration (MH-TRC), co-led by OAHP and Kings Health Partners, provides a coordinated national network between mental health translational and clinical research, industry and charitable partners.
The reach and impact of the work can be seen below: